Postnatal sensitivity of the peripheral chemoreceptors in newborn infants.
نویسندگان
چکیده
The peripheral chemoreflex was tested in healthy term infants by measuring the ventilatory response to 100% oxygen over 30 seconds. Minute ventilation did not change when studied two to six hours after birth. By contrast, at 2-6 days of age a mean decrease of 9.8% was noted, the difference between the groups being highly significant. There were no significant changes in respiratory rate. It is concluded that the chemoreflex is less active immediately after birth than it is a few days later, possibly due to a resetting of the sensitivity of the peripheral chemoreceptors from the fetal state, with its relatively low arterial oxygen tension to the higher postnatal concentrations.
منابع مشابه
Frequency of Profound Congenital Hearing Loss in Healthy Newborn Infants in Fars Province
Introduction Deafness is one of the most important sensory disturbances at birth. Hearing loss can affect the development of speaking and learning during life. Early diagnosis and intervention improve language outcome. The current study aimed to determine the frequency of profound congenital hearing loss in healthy newborn infants in Fars province. Methods In a multicenter prospective study, f...
متن کاملAminophylline and increased activity of peripheral chemoreceptors in newborn infants.
Peripheral chemoreceptor activity was studied in nine healthy, unsedated neonates (with a mean (SD) postconceptional age of 39 (2) weeks and birth weight of 3000 (400) g) by measuring the inhibition of ventilation elicited by five breaths of 100% oxygen (Dejours technique). Changes in tidal volume, frequency, and minute ventilation were measured before and after administration of aminophylline ...
متن کاملCannabinoid receptor expression in peripheral arterial chemoreceptors during postnatal development.
Prenatal exposure to tobacco smoke increases risk of sudden infant death syndrome (SIDS). Marijuana is frequently smoked in conjunction with tobacco, and perinatal exposure to marijuana is associated with increased incidence of SIDS. Abnormalities in peripheral arterial chemoreceptor responses during sleep may be operative in infants at risk for SIDS, and nicotine exposure adversely affects per...
متن کاملPrenatal nicotine exposure up-regulates catecholaminergic traits in peripheral arterial chemoreceptors of newborn rat pups
متن کامل
Effects of Vitamin D in Neonates and Young Infants
Vitamin D is important for the development, growth, and mineralization of the skeletal in neonates and children. Vitamin D is essential for intestinal absorption of calcium. Vitamin D is metabolized to 25-hydroxyvitamin D and then to 1,25-dihydroxyvitamin D. Pregnant women in developed countries often have insufficient serum concentrations of 25-hydroxyvitamin D and a supplementation of vitamin...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Archives of disease in childhood
دوره 62 12 شماره
صفحات -
تاریخ انتشار 1987